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331

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天然化合物

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カタログ番号	製品名	別名	ターゲット
T9929	Ramucirumab		VEGFR
	Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.		VEGFR
T9552	BAZ1A-IN-1		Epigenetic Reader Domain
	BAZ1A-IN-1 is a potent BAZ1A inhibitor with the KD value of 0.52 μM for the BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-survival activity against cancer cell lines with high BAZ1A expression, but weak or no activity ag...		Epigenetic Reader Domain
T2455	PFK-015	PFK15,PFK 015	Glucokinase , Autophagy
	PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).		Glucokinase , Autophagy
T10777	CG347B		HDAC
	CG347B is a selective inhibitor of HDAC6.		HDAC
T8466	BC-DXI-843		Others
	BC-DXI-843 is inhibitor of AIMP2-DX2, and is potential for development of novel therapeutics targeting AIMP2-DX2 in lung cancer.		Others
T2325	Neratinib	HKI-272	EGFR , HER
	Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.		EGFR , HER
T6778	BDA-366		BCL
	BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its antiapoptotic function, thereby transforming it into a pro-ap...		BCL
T8310	MMP-9-IN-1		MMP
	MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).		MMP
T23384	SR 11302		DNA/RNA Synthesis
	SR 11302 is an inhibitor of activator protein-1 (AP-1).		DNA/RNA Synthesis
T8320	J14	J-14	Reactive Oxygen Species
	J-14 is an inhibitor of reversible sulfiredoxin(IC50 : 8.1 μM). J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death		Reactive Oxygen Species
T2345	PTC-209	PTC209,PTC 209	BMI-1 , Autophagy
	PTC-209 is a potent and selective BMI-1 inhibitor.		BMI-1 , Autophagy
T14371	Barasertib	AZD1152	Apoptosis , Aurora Kinase
			Apoptosis , Aurora Kinase
T20533	NNK	Nicotine-derived nitrosamine ketone	Lipoxygenase
	NNK (Nicotine-derived nitrosamine ketone) is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor.		Lipoxygenase
T21588	Olomoucine		ERK , CDK
	Olomoucine is an ATP competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3 and 25 µM, respectively. Olomoucine regulates cell cycle and exhibits an...		ERK , CDK
T9497	Niraparib tosylate monohyrate		PARP
	Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting...		PARP
T28410	PHPS1	PHPS-1,PHPS 1	Phosphatase
	PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.		Phosphatase
T14496	BAMB-4	ITPKA-IN-C14	Others
	BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA). It acts by suppressing the metastasis-promoting effect of ITPKA in lung tumor cells(with IC50 of 37 μM in...		Others
T39275	Befotertinib	D-0316,Befotertinib	EGFR
	Befotertinib (D-0316) is an inhibitor of EGFR tyrosine kinase and can be used for studies about EGFR T790M-positive non-small cell lung cancer.		EGFR
T13044	Mevociclib	SY-1365	CDK
	Mevociclib (SY-1365) is a highly selective covalent inhibitor of CDK7. SY-1365 possesses therapeutic potential in both hematological and solid tumors.		CDK
T9865	Almonertinib mesylate		EGFR
	Almonertinib mesylate is an irreversible inhibitor of EGFR tyrosine kinase with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib mesylate can be used in the non-small cell lung cancer st...		EGFR
T8327	ONO-7475		Trk receptor , TAM Receptor
	ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase		Trk receptor , TAM Receptor
T8756	KRAS inhibitor-9	DUN09716	Apoptosis , Ras
	KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS ...		Apoptosis , Ras
T16996	TAS6417		Apoptosis , EGFR
	TAS6417 is an EGFR inhibitor and is an efficacious drug candidate for patients with NSCLC (IC50: ranging from 1.1-8.0 nM).		Apoptosis , EGFR
T3231	Niraparib	MK-4827	Apoptosis , Others , PARP
	Niraparib (MK-4827) is a PARP inhibitor that selectively inhibits PARP1 and PARP2 (IC50=3.8/2.1 nM). Niraparib has antitumor activity, inhibits DNA damage repair, and induces apoptosis.		Apoptosis , Others , PARP
T2542	Prucalopride	R-93877	5-HT Receptor
	Prucalopride (R-93877) is a selective, high-affinity 5-HT4A/4B receptor agonist (Ki: 2.5/8 nM). It has >290-fold selectivity for 5-HT4A/4B receptor than other 5-HT receptor subtypes.		5-HT Receptor
T60076	Oritinib	SH-1028	EGFR
	Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can ...		EGFR
T16545	Pivanex	Pivalyloxymethyl butyrate,AN-9	Apoptosis , HDAC , Bcr-Abl
	Pivanex (Pivalyloxymethyl butyrate) is an orally active HDAC inhibitor and an antimetastatic and antiangiogenic agent. Pivanex downregulates the Bcr-Abl protein and enhances apoptosis.		Apoptosis , HDAC , Bcr-Abl
T5462	Almonertinib	HS-10296	EGFR
	Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.		EGFR
T0459	Sulindac	Arthrocine,MK-231,Clinoril,Sulindac sulfoxide	COX , Autophagy
	Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity. Converted in vivo to an active metabolite, sulindac, a nonsteroidal anti-inflammatory drug (NSAID), blocks cycl...		COX , Autophagy
T8656	CAY10404	3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T	Apoptosis , Akt , COX
	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel...		Apoptosis , Akt , COX
T5675	Almonertinib hydrochloride	HS-10296 hydrochloride	EGFR
	Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.		EGFR
T1602	Valproic acid sodium salt	Sodium Valproate	Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy
	Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha...
T3353	Niraparib hydrochloride	MK-4827 hydrochloride,MK-4827 (hydrochloride)	Apoptosis , Others , PARP
	Niraparib hydrochloride (MK-4827 hydrochloride) is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. Niraparib hydrochloride inhibits PARP activity, enhancing the accumulation of...		Apoptosis , Others , PARP
T9533	BC-LI-0186	4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide	Others
	BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) is a potent and selective inhibitor of the interaction of Leucyl-tRNA synthetase (LRS) and Ras-related GTP-binding protei...		Others
T2602	Barasertib-HQPA	1H-Pyrazole-3-acetamide,Barasertib,AZD1152-HQPA,AZD2811,AZD1152-HQPA\|AZD2811	Apoptosis , Aurora Kinase
	Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.		Apoptosis , Aurora Kinase
T6474	Divalproex Sodium	Valproate semisodium,Epival	HDAC
	Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme...		HDAC
T0373	Erlotinib	OSI-744,NSC 718781,CP358774,R1415	EGFR , Autophagy
	Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.		EGFR , Autophagy
T9003	CVT-11127		Dehydrogenase
	CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.		Dehydrogenase
T21312	Afatinib	Afatinib free base,BIBW 2992	EGFR , Autophagy
	Afatinib (BIBW 2992) is an irreversible inhibitor of EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R/T790M and HER2 with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM , respectively).		EGFR , Autophagy
T6892	Niraparib tosylate	MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate	Apoptosis , PARP
	Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.		Apoptosis , PARP
T1773	Afatinib Dimaleate	BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate	EGFR , HER , Autophagy
	Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic act...		EGFR , HER , Autophagy
T9304	(S)-Sunvozertinib	N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide,DZD9008	EGFR , HER
	(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.		EGFR , HER
T6178	PTC-209 hydrobromide	PTC-209 HBr	BMI-1 , Autophagy
	PTC-209 hydrobromide (PTC-209 HBr) is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of cancer-initiating cells (CICs).		BMI-1 , Autophagy
T1758	ABT-751	E7010	Microtubule Associated , Autophagy
	ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.		Microtubule Associated , Autophagy
T7351	3-Methylcytidine		Nucleoside Antimetabolite/Analog
	3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.		Nucleoside Antimetabolite/Analog
T13602	CDDO-2P-Im	CDDO-2-P-Im	Others
	CDDO-2P-Im shows chemopreventive effect and reduces the size and severity of the lung tumors in the mouse lung cancer model.		Others
T35329L	EAD1 TFA(1644388-26-0 Free base)	EAD1 HCL(1644388-26-0 Free base)	Apoptosis , Autophagy
	EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL also induces apoptosis		Apoptosis , Autophagy
T30087	Antroquinonol		Reactive Oxygen Species , Nrf2
	Antroquinonol is a ubiquinone derivative from Antrodia camphorata with anti-inflammatory and anticancer activities.Antroquinonol reduces oxidative stress and inhibits inflammation and sclerosis in mice with focal segment...		Reactive Oxygen Species , Nrf2
T7082	HDAC8-IN-1		HDAC
	MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits ...		HDAC
T23867	Cdc7-IN-7c	Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c	CDK
	Cdc7-IN-7c (Cdc7 inhibitor-7c) has antitumor activity and has inhibitory effect on liver cancer, lung cancer, kidney cancer, brain cancer and cervical cancer.		CDK

Compounds

Target: Epigenetic Reader Domain

PFK-015

T2455

Synonym: PFK15,PFK 015

Target: Glucokinase, Autophagy

Target: DNA/RNA Synthesis

J14

T8320

Synonym: J-14

Target: Reactive Oxygen Species

PTC-209

T2345

Synonym: PTC209,PTC 209

Target: BMI-1, Autophagy

Barasertib

T14371

Synonym: AZD1152

Target: Apoptosis, Aurora Kinase

NNK

T20533

Synonym: Nicotine-derived nitrosamine ketone

Niraparib tosylate monohyrate

Synonym: PHPS-1,PHPS 1

Target: Phosphatase

BAMB-4

T14496

Synonym: ITPKA-IN-C14

Target: Others

Befotertinib

T39275

Synonym: D-0316,Befotertinib

Almonertinib mesylate

Target: Trk receptor, TAM Receptor

KRAS inhibitor-9

T8756

Synonym: DUN09716

Target: Apoptosis, Ras

TAS6417

T16996

Synonym:

Target: Apoptosis, EGFR

Niraparib

T3231

Synonym: MK-4827

Target: Apoptosis, Others, PARP

Prucalopride

T2542

Synonym: R-93877

Target: 5-HT Receptor

Synonym: Pivalyloxymethyl butyrate,AN-9

Target: Apoptosis, HDAC, Bcr-Abl

Synonym: Arthrocine,MK-231,Clinoril,Sulindac sulfoxide

Target: COX, Autophagy

CAY10404

T8656

Synonym: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T

Target: Apoptosis, Akt, COX

Almonertinib hydrochloride

T5675

Synonym: HS-10296 hydrochloride

Target: EGFR

Valproic acid sodium salt

T1602

Synonym: Sodium Valproate

Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, HDAC, Autophagy

Niraparib hydrochloride

T3353

Synonym: MK-4827 hydrochloride,MK-4827 (hydrochloride)

Target: Apoptosis, Others, PARP

BC-LI-0186

T9533

Synonym: 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide

Target: Others

Barasertib-HQPA

T2602

Synonym: 1H-Pyrazole-3-acetamide,Barasertib,AZD1152-HQPA,AZD2811,AZD1152-HQPA|AZD2811

Target: Apoptosis, Aurora Kinase

Divalproex Sodium

T6474

Synonym: Valproate semisodium,Epival

Target: HDAC

Erlotinib

T0373

Synonym: OSI-744,NSC 718781,CP358774,R1415

Target: EGFR, Autophagy

CVT-11127

T9003

Synonym:

Target: Dehydrogenase

Afatinib

T21312

Synonym: Afatinib free base,BIBW 2992

Target: EGFR, Autophagy

Niraparib tosylate

T6892

Synonym: MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate

Target: Apoptosis, PARP

Afatinib Dimaleate

T1773

Synonym: BIBW2992,Afatinib,BIBW 2992MA2,Afatinib (BIBW2992) Dimaleate

Target: EGFR, HER, Autophagy

(S)-Sunvozertinib

T9304

Synonym: N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide,DZD9008

Target: BMI-1, Autophagy

ABT-751

T1758

Synonym: E7010

Target: Microtubule Associated, Autophagy

3-Methylcytidine

T7351

Synonym:

Target: Nucleoside Antimetabolite/Analog

EAD1 TFA(1644388-26-0 Free base)

T35329L

Synonym: EAD1 HCL(1644388-26-0 Free base)

Target: Apoptosis, Autophagy

Antroquinonol

T30087

Synonym:

Target: Reactive Oxygen Species, Nrf2

Synonym: Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c

Target: CDK

カタログ番号	製品名	別名	ターゲット
T3862	Irigenin		NF-κB , Integrin
	Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha...		NF-κB , Integrin
TN1153	Polyporenic acid C		Apoptosis , PARP , Caspase , PI3K
	Polyporenic acid C shows inhibitory activity against human collagenase.		Apoptosis , PARP , Caspase , PI3K
T5739	Paederosidic acid		Apoptosis , BCL
	Paederosidic acid has significant anti-tumor, anticonvulsant and sedative effects. Paederosidic acid increases brain gamma-aminobutyric acid and decreases glutamic acid in the brain, and it up-regulates expressions of GA...		Apoptosis , BCL
T5061	Lumichrome	7,8-Dimethylalloxazine	Others
	Lumichrome (7,8-Dimethylalloxazine) is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at nanomolar concentrations. Lumichrom...		Others
T4S1173	Agrimol B		Sirtuin , PPAR
	1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.		Sirtuin , PPAR
T1181	Gefitinib	ZD1839	EGFR , Tyrosine Kinases , Autophagy
	Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell...		EGFR , Tyrosine Kinases , Autophagy
T2870	Matrine	Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine	Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
	Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.		Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
T7064	Valproic Acid	Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid	Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy
	Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
T2S0618	β-Elemonic Acid	3-oxo Tirucallic Acid,Beta-Elemonic acid,3-Oxotirucallenoic Acid,Elemadienonic Acid	Apoptosis , Reactive Oxygen Species , COX
	β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are rel...		Apoptosis , Reactive Oxygen Species , COX
T19581	Tiglyl carnitine		Endogenous Metabolite
	Tiglyl carnitine is associated with lung cancer and carnitine and glycine to 3-ketothiolase deficiency .		Endogenous Metabolite
TN1143	1-O-Acetyl britannilactone		NF-κB , COX
	1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling.		NF-κB , COX
T25192	Butyrolactone I	Olomoucin	CDK
	Butyrolactone I (Olomoucin) is an ATP-competitive inhibitor of CDK and cdc2 kinase family. Butyrolactone I shows antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines.		CDK
T7849	Norspermine		Others
	Norspermine is a polyamine analogue ,used in the treatment of non-small cell lung carcinoma and breast cancer.		Others
TJS0339	Coumarin-3-carboxylic acid	3-Carboxycoumarin	VEGFR
	The combination of Valproic acid with Coumarin-3-carboxylic acid (3-Carboxycoumarin) suppresses the proliferation and migration of lung cancer cells via EGFR/VEGFR2/c-Met-Akt-NF-κB signaling pathways; this combination ma...		VEGFR
T7990	9-hydroxy-4-androstene-3,17-dione		Others
	9-hydroxy-4-androstene-3,17-dione is a steroid hormone. It has anti-tumor activity and can inhibit the growth of many types of cancer cells, including breast, prostate and lung cancer cells.		Others
TN6771	Malabaricone B		Others
	Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.		Others
TJP2872	Acevaltrate	Acevaltratum,Acetoxyvaltrate	ATPase , Others
	1. Acevaltrate (Acevaltratum) displays high cytotoxicity against GLC(4), a human small-cell lung cancer cell line, and against COLO 320, a human colorectal cancer cell line, with IC50 values of 1-6 uM.		ATPase , Others
T5646	Cinnamic acid	3-Phenylacrylic acid,β-Phenylacrylic acid	Endogenous Metabolite
	Cinnamic acid (β-Phenylacrylic acid) has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung ca...		Endogenous Metabolite
T5S1982	Periplocin	Periplocoside	Apoptosis , Others
	1. Periplocin (Periplocoside) has anti-cancer effects on lung cancer cells, induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. 2. Periplocin is used for treatment of rheumato...		Apoptosis , Others
T4S0998	Trifolirhizin		TNF , Tyrosinase
	Trifolirhizin exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis, and therefore, are candidates as skin-whitening agents.Trifolirhizin possesses potential anti-inflammatory and anti-cancer ...		TNF , Tyrosinase
TMA2474	δ-Tocotrienol	Delta-Tocotrienol	ERK , BCL , VEGFR , Akt , PI3K , PDK , p53
	δ-Tocotrienol (Delta-Tocotrienol) is a potential angiogenic inhibitor. δ-Tocotrienol is also a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSC-LC) cell proliferation, induce apoptosis...		ERK , BCL , VEGFR , Akt , PI3K , PDK , p53
TN1393	(-)-Anonaine		Apoptosis , Antioxidant , Parasite , Antifungal
	(-)-Anonaine can be extracted from several species of Magnoliaceae and Annelidae and has antimalarial, antibacterial, antifungal, antioxidant, anticancer, antidepressant and vasodilatory activities. (-)-Anonaine induces ...		Apoptosis , Antioxidant , Parasite , Antifungal
TN1721	Gypenoside L		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
	Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a...		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
T7027	EURYCOMANONE	Pasakbumin A	Others
	Eurycomanone (Pasakbumin A) is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibits A549 lung cancer cell p...		Others
T75643	Isoxanthohumol		HSV
	Isoxanthohumol is a prenylated flavonoid derived from hops and beer with antiproliferative activity against several human cancer cell lines.Isoxanthohumol inhibits the metastasis or invasion of lung metastases of tumor c...		HSV
T1660	Silibinin	Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species , Autophagy
	Silibinin (Silybin) is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin an...		Reactive Oxygen Species , Autophagy
T5679	(E)-Ferulic acid	trans-Ferulic acid,(E)-Coniferic acid	BCL , Ferroptosis , Wnt/beta-catenin , Endogenous Metabolite
	(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pr...
T0186	Docetaxel trihydrate	RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate	Apoptosis , BCL , Microtubule Associated
			Apoptosis , BCL , Microtubule Associated
TN3972	Epimedokoreanin B		Apoptosis , Others , Antibacterial
	Epimedokoreanin B (EKB), an isoprenylated flavonoid isolated from Korean Epimedium, exhibited anticancer activity in human non-small cell lung cancer (NSCLC) A549 and NCI-H292 cells.Epimedokoreanin B also possesses anti-...		Apoptosis , Others , Antibacterial
T15011	Creatine riboside		Others
	Creatine riboside, a urinary metabolite, is a diagnostic and prognostic biomarker of lung cancer.		Others
TN1889	Lupalbigenin		ERK , Akt , Topoisomerase
	Lupalbigenin sensitizes detachment-induced cell death in human lung cancer cell through down-regulation of pro-survival proteins.		ERK , Akt , Topoisomerase
TN4603	Myricanol		BCL , VEGFR , Caspase , HIF
	Myricanol can elicit growth inhibitory and cytotoxic effects on lung cancer cells, it can significantly decelerate tumor growth in vivo by inducing apoptosis.		BCL , VEGFR , Caspase , HIF
T40708	Neoanhydropodophyllol
	Neoanhydropodophyllol, a cyclolignan derivative, exhibits potent antineoplastic activity by exerting cytotoxic effects on various cancer cell lines including leukemia, lung carcinoma, and colon carcinoma.
TN4352	Jatamanvaltrate B		Others
	Jatamanvaltrate B shows cytotoxicity against lung adenocarcinoma (A549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8),and hepatoma (Bel7402) cell lines.		Others
TN5684	5,6-Desmethylenedioxy-5-methoxyaglalactone
	5,6-Desmethylenedioxy-5-methoxyaglalactone is cytotoxic to small cell lung cancer (NCI-H187) cell line. It has antimycobacterial activity against Mycobacterium tuberculosis H(37)Ra.
T3425	Polyphyllin G	Polyphyllin VII,Polyphyllin VII,Y-0166	Others
	Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, cervical cancer, hepatocel...		Others
TN3646	Chlorovaltrate K		Others
	Chlorovaltrate K shows moderate cytotoxicity against lung adenocarcinoma (A 549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8) and hepatoma (Bel 7402) cell lines with IC50 values of 0.89-9.76 uM.		Others
TN3424	Antiquorin		Others
	Antiquorin exhibits moderate cytotoxic activities against the human lung cancer 95-D cell line with the IC50 value of 34.5 uM.		Others
TN3560	Cabralealactone		Antifection
	Cabralealactone displays antimycobacterial activity against Mycobacterium tuberculosis, it is weakly cytotoxic to a breast cancer (BC) cell line, it is moderately active against a small-cell lung cancer (NCI-H187) cell l...		Antifection
TN6062	1,3,9-Trimethyluric acid
	1,3,9-Trimethyluric acid exhibits in vitro cytotoxic activity against breast cancer (MCF-7), human neuroblastoma (SHSY5Y), human non-small cell lung cancer (A549) and human liver cancer (HEPG2) with IC50 value in the ran...
TN5249	Volvaltrate B		Others
	Volvaltrate B shows cytotoxic activity against the lung adenocarcinoma (A549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8), and hepatoma (Bel7402) cell lines, with IC50 values of 8.5, 2.0, 3.2, and 6.1 uM, r...		Others
TN4261	Isoaltenuene		Antifection
	Isoaltenuene shows antibiotic activity against Gram-positive bacteria; it also shows a minor phytotoxic activity on tomato leaves at level of 20 ug/spot . Isoaltenuene exhibits cytotoxic activity against lung cancer cell...		Antifection
TN3355	Agatharesinol acetonide		Antifection
	Agatharesinol acetonide shows anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM).		Antifection
TN1872	Linderone		Others
	Linderone A shows anticancer activity against A549 non-small cell lung cancer cells and PC-3 prostate adenocarcinoma cell line.		Others
TN1642	Ferruginol		BCL , PARP , Caspase
	Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic, cardioprotective, anticancer, anti-oxidative and anti-inflammatory activities, it can induce apoptosis in non-small cell lung cancer (NSCLC) cells.		BCL , PARP , Caspase
TN4355	Jolkinol A		Others
	Jolkinol A can inhibit both MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) cell lines, with GI50 values ranging between 40.9 microM and 95.3 microM.		Others
TN2493	1,4,5,6-Tetrahydroxy-7-prenylxanthone		Others
	1,4,5,6-Tetrahydroxy-7-prenylxanthone has anti-cancer activity, it shows moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines; it also exhibits moderate activities with GI...		Others
TN4166	Griffipavixanthone		ERK , Raf , ROS , MEK , Caspase
	Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS productio...		ERK , Raf , ROS , MEK , Caspase
TN2492	1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone		Others
	1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone has moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacks antifungal activity against Candida albicans.		Others
T83110	Angulatin K
	Angulatin K, a sesquiterpene polyol ester naturally occurring in the root bark of Celastrus angulatus [1], exhibits anti-cancer properties effective against a variety of solid tumors, including renal, breast, and lung.
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天然物製品

Irigenin

T3862

Synonym:

Target: NF-κB, Integrin

Polyporenic acid C

TN1153

Synonym:

Target: Apoptosis, PARP, Caspase, PI3K

Paederosidic acid

T5739

Synonym:

Target: Apoptosis, BCL

Lumichrome

T5061

Synonym: 7,8-Dimethylalloxazine

Target: Sirtuin, PPAR

Gefitinib

T1181

Synonym: ZD1839

Target: EGFR, Tyrosine Kinases, Autophagy

Matrine

T2870

Synonym: Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine

Target: Mitophagy, Ferroptosis, Opioid Receptor, Autophagy

Valproic Acid

T7064

Synonym: Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid

Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy

β-Elemonic Acid

T2S0618

Synonym: 3-oxo Tirucallic Acid,Beta-Elemonic acid,3-Oxotirucallenoic Acid,Elemadienonic Acid

Target: Apoptosis, Reactive Oxygen Species, COX

Tiglyl carnitine

T19581

Synonym:

Target: Endogenous Metabolite

1-O-Acetyl britannilactone

Coumarin-3-carboxylic acid

TJS0339

Synonym: 3-Carboxycoumarin

Target: VEGFR

9-hydroxy-4-androstene-3,17-dione

Synonym: Acevaltratum,Acetoxyvaltrate

Target: ATPase, Others

Cinnamic acid

T5646

Synonym: 3-Phenylacrylic acid,β-Phenylacrylic acid

Target: Endogenous Metabolite

Periplocin

T5S1982

Synonym: Periplocoside

Target: Apoptosis, Others

Trifolirhizin

T4S0998

Synonym:

Target: TNF, Tyrosinase

δ-Tocotrienol

TMA2474

Synonym: Delta-Tocotrienol

Target: ERK, BCL, VEGFR, Akt, PI3K, PDK, p53

(-)-Anonaine

TN1393

Synonym:

Target: Apoptosis, Antioxidant, Parasite, Antifungal

Gypenoside L

TN1721

Synonym:

Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS

EURYCOMANONE

T7027

Synonym: Pasakbumin A

Synonym: Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

(E)-Ferulic acid

T5679

Synonym: trans-Ferulic acid,(E)-Coniferic acid

Target: BCL, Ferroptosis, Wnt/beta-catenin, Endogenous Metabolite

Docetaxel trihydrate

T0186

Synonym: RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate

Target: Apoptosis, BCL, Microtubule Associated

Epimedokoreanin B

TN3972

Synonym:

Target: Apoptosis, Others, Antibacterial

Target: ERK, Akt, Topoisomerase

Myricanol

TN4603

Synonym:

Target: BCL, VEGFR, Caspase, HIF

Neoanhydropodophyllol

5,6-Desmethylenedioxy-5-methoxyaglalactone

Synonym: Polyphyllin VII,Polyphyllin VII,Y-0166

1,3,9-Trimethyluric acid

Agatharesinol acetonide

Target: BCL, PARP, Caspase

1,4,5,6-Tetrahydroxy-7-prenylxanthone

Target: ERK, Raf, ROS, MEK, Caspase

1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01593	CT83 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	CT83 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-01594	CT83 Protein-VLP, Human, Recombinant (His)	Human	HEK293 Cells
	CT83 Protein-VLP, Human, Recombinant (His) is expressed in HEK293.
TMPH-01357	ALDOA Protein, Human, Recombinant (His)	Human	E. coli
	Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein. ALDOA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted...
TMPJ-00281	CADM1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. C...
TMPY-03958	TGF alpha Protein, Human, Recombinant	Human	E. coli
	The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain)	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPY-02028	RON/CD136 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	The tyrosine kinase receptor, macrophage-stimulating 1 receptor (MST1R), a c-met-related tyrosine kinase, also known as the Ron receptor or CD136, controls cell survival and motility programs related to invasive growth. ...
TMPY-00539	GSTA1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) ...
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPY-03856	SEZ6L2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SEZ6L2, also known as PSK-1, belongs to the SEZ6 family. It contains 3 CUB domains and 5 Sushi (CCP/SCR) domains. SEZ6L2 may contribute to specialized endoplasmic reticulum functions in neurons.SEZ6L2 presents on the sur...
TMPY-04321	CHRNA5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in ...
TMPK-01188	CHODL Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	chondrolectin (CHODL) is commonly overexpressed in the majority of lung cancers, indicating a possible correlation between CHODL and metastasis of lung cancer cells. the expression of CHODL is significantly decreased in ...
TMPK-00906	PSCA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s...
TMPK-00728	PSCA Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s...
TMPJ-01288	KLF6 Protein, Human, Recombinant	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ...
TMPK-01204	TNFRSF19 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for na...
TMPK-01299	CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His)	Cynomolgus	HEK293 Cells
	Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at meta...
TMPK-01203	TNFRSF19 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	A novel susceptibility gene TNFRSF19, which encodes an orphan member of the TNF receptor superfamily known to be associated with nasopharyngeal carcinoma (NPC) and lung cancer risk. TNFRSF19, a susceptibility gene for na...
TMPY-03416	TNFAIP8 Protein, Human, Recombinant (His)	Human	E. coli
	Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-al...
TMPK-01034	SEMA4B Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling p...
TMPY-03398	FHIT Protein, Human, Recombinant (His)	Human	E. coli
	Fragile histidine triad, also known as FHIT, may play a key role in differentiating humans from apes. Fragile histidine triad gene belongs to the histidine triad gene family. It has been shown that fragile histidine tria...
TMPY-04686	SHISA3 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	SHISA3(high)CLL are characterized by a restrained activation of Wnt signaling and sensibility to lenalidomide-induced apoptosis. SHISA3 promoter hypermethylation might increase the risk of LSCC through regulation of gene...
TMPK-00340	ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPJ-01262	UPRT Protein, Human, Recombinant (His)	Human	E. coli
	UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion o...
TMPK-00339	ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-00341	ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPJ-00160	EMMPRIN/CD147 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane ...
TMPY-03601	PDRG1 Protein, Human, Recombinant (His)	Human	E. coli
	PDRG1, also known as C2orf126, belongs to the prefoldin subunit beta family. It is predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. PDRG1 may play a role in chapero...
TMPY-03287	RRM1 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	RRM1 is a subunit of ribonucleoside-diphosphate reductase which is constituted by two subunits. Ribonucleoside-diphosphate reductase is an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesi...
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His)	Human	HEK293 Cells
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...
TMPJ-01195	BTNL9 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Butyrophilin-Like Protein 9 (BTNL9) is single-pass type I membrane protein member of the BTN/MOG family that belongs to the immunoglobulin superfamily. BTNL9 consists of two domains: one B30.2/SPRY domain and one Ig-like...
TMPJ-01194	BTNL9 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Butyrophilin-Like Protein 9 (BTNL9) is single-pass type I membrane protein member of the BTN/MOG family that belongs to the immunoglobulin superfamily. BTNL9 consists of two domains: one B30.2/SPRY domain and one Ig-like...
TMPY-02399	TRF1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Telomeric repeat binding factor 1 (TRF1), also known as TERF1, the shelterin complex, which modulates the telomere structures. TRF1 protein structure contains a C-terminal Myb motif, a dimerization domain near its N-term...
TMPJ-01209	BTNL9 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Butyrophilin-Like Protein 9 (BTNL9) is single-pass type I membrane protein member of the BTN/MOG family that belongs to the immunoglobulin superfamily. BTNL9 consists of two domains: one B30.2/SPRY domain and one Ig-like...
TMPY-04375	Casein Kinase 1 alpha Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to theprotein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein k...
TMPY-04484	ACK1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	ACK1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell types. This downstream effector of CDC42 mediates CDC42-dependent cell mig...
TMPY-03397	TPPP3 Protein, Human, Recombinant (His)	Human	E. coli
	TPPP3, a member of the Tubulin polymerization-promoting protein family, is an intrinsically unstructured protein that induces tubulin polymerization. TPPP3 is a marker in the developing musculoskeletal system. In tendons...
TMPY-02100	TEM7 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Plexin domain-containing protein 1, also known as tumor endothelial marker 3, tumor endothelial marker 7 and PLXDC1 and TEM3, is a secreted, cytoplasm and single-pass type I membrane protein that belongs to the plexin fa...
TMPY-04084	ANGPTL1 Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an im...
TMPY-02796	KIAA0101 Protein, Human, Recombinant (His)	Human	E. coli
	KIAA11, also known as p15(PAF), is a proliferating cell nuclear antigen-associated factor that interacts with proliferating cell nuclear antigen(PCNA). It was initially isolated in a yeast two-hybrid screen for PCNA bind...
TMPJ-01212	ULBP-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2...
TMPY-02757	TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Fn14 shares 82% amino acid identity with the mouse sequence. It contains a signal peptide, an ext...
TMPY-04417	DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)	Human	Baculovirus Insect Cells
	Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK...
TMPY-02228	P53 Protein, Cynomolgus, Recombinant	Cynomolgus	E. coli
	p53, also known as Tp53, is a DNA-binding protein which belongs to the p53 family. It contains transcription activation, DNA-binding, and oligomerization domains. p53 protein is expressed at low level in normal cells and...
TMPH-03753	MYLK Protein, Human, Recombinant (His)	Human	E. coli
	Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phos...

CT83 Protein, Human, Recombinant (E. coli, His)

TMPH-01593

Species: Human

Expression System: E. coli

CT83 Protein-VLP, Human, Recombinant (His)

TMPH-01594

Species: Human

Expression System: HEK293 Cells

ALDOA Protein, Human, Recombinant (His)

TMPH-01357

Species: Human

Expression System: E. coli

CADM1 Protein, Mouse, Recombinant (hFc)

TMPJ-00281

Species: Mouse

Expression System: HEK293 Cells

TGF alpha Protein, Human, Recombinant

TMPY-03958

Species: Human

Expression System: E. coli

MMP-12 Protein, Human, Recombinant (catalytic domain)

TMPY-02869

Species: Human

Expression System: E. coli

RON/CD136 Protein, Human, Recombinant (His)

TMPY-02028

Species: Human

Expression System: HEK293 Cells

GSTA1 Protein, Human, Recombinant (His)

TMPY-00539

Species: Human

Expression System: HEK293 Cells

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

TMPJ-00412

Species: Human

Expression System: HEK293 Cells

SEZ6L2 Protein, Human, Recombinant (His)

TMPY-03856

Species: Human

Expression System: HEK293 Cells

CHRNA5 Protein, Human, Recombinant (His)

TMPY-04321

Species: Human

Expression System: HEK293 Cells

CHODL Protein, Human, Recombinant (hFc)

TMPK-01188

Species: Human

Expression System: HEK293 Cells

PSCA Protein, Mouse, Recombinant (hFc)

TMPK-00906

Species: Mouse

Expression System: HEK293 Cells

PSCA Protein, Human, Recombinant (hFc)

TMPK-00728

Species: Human

Expression System: HEK293 Cells

KLF6 Protein, Human, Recombinant

TMPJ-01288

Species: Human

Expression System: E. coli

TNFRSF19 Protein, Human, Recombinant (His)

TMPK-01204

Species: Human

Expression System: HEK293 Cells

CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His)

TMPK-01299

Species: Cynomolgus

Expression System: HEK293 Cells

TNFRSF19 Protein, Human, Recombinant (hFc)

TMPK-01203

Species: Human

Expression System: HEK293 Cells

TNFAIP8 Protein, Human, Recombinant (His)

TMPY-03416

Species: Human

Expression System: E. coli

SEMA4B Protein, Mouse, Recombinant (His)

TMPK-01034

Species: Mouse

Expression System: HEK293 Cells

FHIT Protein, Human, Recombinant (His)

TMPY-03398

Species: Human

Expression System: E. coli

SHISA3 Protein, Human, Recombinant (mFc)

TMPY-04686

Species: Human

Expression System: HEK293 Cells

ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00340

Species: Human

Expression System: HEK293 Cells

UPRT Protein, Human, Recombinant (His)

TMPJ-01262

Species: Human

Expression System: E. coli

ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-00339

Species: Mouse

Expression System: HEK293 Cells

ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

TMPK-00341

Species: Human

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant (His)

TMPJ-00160

Species: Human

Expression System: HEK293 Cells

PDRG1 Protein, Human, Recombinant (His)

TMPY-03601

Species: Human

Expression System: E. coli

RRM1 Protein, Human, Recombinant (His & GST)

TMPY-03287

Species: Human

Expression System: Baculovirus Insect Cells

IL-32 Protein, Human, Recombinant (isoform alpha, His)

TMPY-01033

Species: Human

Expression System: HEK293 Cells

BTNL9 Protein, Human, Recombinant (His)

TMPJ-01195

Species: Human

Expression System: HEK293 Cells

BTNL9 Protein, Human, Recombinant (hFc)

TMPJ-01194

Species: Human

Expression System: HEK293 Cells

TRF1 Protein, Human, Recombinant (His)

TMPY-02399

Species: Human

Expression System: Baculovirus Insect Cells

BTNL9 Protein, Mouse, Recombinant (hFc)

TMPJ-01209

Species: Mouse

Expression System: HEK293 Cells

Casein Kinase 1 alpha Protein, Human, Recombinant (GST)

TMPY-04375

Species: Human

Expression System: Baculovirus Insect Cells

ACK1 Protein, Human, Recombinant (GST)

TMPY-04484

Species: Human

Expression System: Baculovirus Insect Cells

TPPP3 Protein, Human, Recombinant (His)

TMPY-03397

Species: Human

Expression System: E. coli

TEM7 Protein, Human, Recombinant (His)

TMPY-02100

Species: Human

Expression System: HEK293 Cells

ANGPTL1 Protein, Canine, Recombinant (hFc)

TMPY-04084

Species: Canine

Expression System: HEK293 Cells

KIAA0101 Protein, Human, Recombinant (His)

TMPY-02796

Species: Human

Expression System: E. coli

ULBP-1 Protein, Mouse, Recombinant (His)

TMPJ-01212

Species: Mouse

Expression System: HEK293 Cells

TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)

TMPY-02757

Species: Human

Expression System: HEK293 Cells

DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)

TMPY-04417

Species: Human

Expression System: Baculovirus Insect Cells

p53 Protein, Cynomolgus, Recombinant

TMPY-02228

Species: Cynomolgus

Expression System: E. coli

MYLK Protein, Human, Recombinant (His)

TMPH-03753

Species: Human

Expression System: E. coli

カタログ番号	製品名
L2190	Anti-Lung Cancer Compound Library	1702 compounds
	A unique collection of 1702 compounds with anti-lung cancer therapeutic activity or targeting lung cancer’s major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study；
L2192	Anti-Pancreatic Cancer Compound Library	2238 compounds
	A unique collection of 2238 pancreatic cancer related compounds can be used in HTS and HCS;
L4300	Wnt/Hedgehog/Notch Compound Library	237 compounds
	A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L2191	Anti-Breast Cancer Compound Library	1939 compounds
	A unique collection of 1939 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study；
L4600	Selected Plant-Sourced Compound Library	3048 compounds
	A unique collection of 3048 plant-sourced compounds that derived from 277 plant species for high throughput screening (HTS) and high content screening (HCS);

ライブラリー

Anti-Lung Cancer Compound Library

L2190

Compounds: 1702

Anti-Pancreatic Cancer Compound Library

L2192

Compounds: 2238

Wnt/Hedgehog/Notch Compound Library

L4300

Compounds: 237

Anti-Breast Cancer Compound Library

L2191

Compounds: 1939

Selected Plant-Sourced Compound Library

L4600

Compounds: 3048